Solid and polycystic patternを呈した巨大副腎皮質癌の1例

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  • AN ADULT CASE OF GIANT VIRILIZING ADRENOCORTICAL CARCINOMA WITH SOLID AND POLYCYSTIC PATTERN

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We report an adult patient with virilizing adrenocortical carcinoma and review of the literature reported in Japan. The patient sought medical advice for amenorrhea. A huge retroperitoneal mass was detected in the right abdomen by ultrasonography. Serum concentrations of various hormones were normal. Abdominal CT and MRI revealed that the tumor was heterogeneous, and was composed of both a solid part with massive calcification and a polycystic part. At laparotomy, there was mild fibrous adhesion but no invasion to the surrounding tissues. The resected tumor weighed 1640g and measured 20×10×7.5cm in size. Macroscopically, the tumor contained bone and fat tissue and the cystic part serous fluid. A diagnosis of adrenocortical carcinoma was made by pathological and immunohisto-chemical examinations. In all other 13 cases previously reported, the tumors consisted only of a solid component without any cystic formation. This case was unique in that the tumor showed a combination of solid and polycystic patterns.

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