原発性両側乳癌症例の臨床的検討

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  • CLINICOPATHOLOGICAL STUDY OF PRIMARY BILATERAL BREAST CANCER

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In a series of 709 patients with breast cancer operated on at the department in a recent three decades from 1968 to 1998, there were 33(4.7%) patients with primary bilateral breast cancer. Eleven patients(1.6%) had synchronous and 22 patients(3.1%) had metachronous bilateral breast cancers. These 33 patients were clinicopathologically compared with those having unilateral breast cancer.<br> Average age at operation for the first cancer in metachronous patients was 42.9 years, that was significant younger than others. Patients with bilateral breast cancer had history of familial cancer or other multiple primary cancers in a high frequency. In metachronous patients 80% of them found the second cancer by themselves, which 27% of synchronous patients found it by themselves, with a significant difference. The 5-year survival rates were 86.9%, 88.9% and 76.7% in unilateral cases, synchronous cases and metachronous cases, respectively. Therefore, we have recognized the importance of early discovery and treatment of contralateral breast cancer.

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