口腔機能と老化に関する研究　　痴呆の危険要因に関する疫学的検討

DOI 被引用文献11件 参考文献14件

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タイトル別名
  • A Study on Oral Function and Aging. An Epidemiological Risk Factor for Dementia.
  • An Epidemiological Risk Factor for Dementia
  • 痴呆の危険要因に関する疫学的検討

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A case-control study was performed to evaluate the loss of teeth as a potential risk factor for dementia. Dementia subjects were 36 patients (mean age: 79.3±8.3years) with dementia of the Alzheimer-type (DAT) and 39 patients (79.5 ± 6.3) with vascular dementia (VD). A diagnosis of DAT and VD was made according to the NINCDS-ADRDA criteria by the same neurologist. Age-matched controls (77.9±6.4) were 78 residents without dementia in a nursing home. To assess the extent of dementia, dementia subjects were evaluated for duration of dementia onset by Hasegawa's Dementia Scale Revised version (HDS-R), Gottfries Brane Steen Scale (GBS), Activities of Daily Living (ADL), and Cella Media Index (CMI).<BR>There were no statistical differences between DAT and VD in duration of dementia onset by HDS-R, GBS, ADL, and CMI. There were fewer teeth in the DAT group than the VD group. A significant dose-response relation between the risk of dementia and the number of teeth was noted in DAT, but not in VD. The results suggested that the loss of teeth may be one of the risk factors for DAT.

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