書誌事項
- タイトル別名
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- Candidate gene analysis of nonsyndromic cleft in humans: transforming growth factor alpha.
- transforming growth factor alpha
- 形質転換増殖因子α (TGFA) について
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抄録
Previous association studies of nonsyndromic cleft lip with or without cleft palate in Caucasian have strongly suggested that transforming growth factor alpha (TGFA) plays a role in clef ting. However, this remains controversial.<BR>Purpose: The aim of this study was (1) to analyze and reconfirm the role of TGFA in Japanese and (2) to summarize the results of previous genetic studies of nonsyndromic cleft.<BR>Method: We studied TFGA Taq I and two newly detected polymorphism makers for TGFA.<BR>Results and conclusion: Highly significant associations were found between the haplotypes of the two new TGFA makers in Japanese. Our haplotype data support the role of TGFA in facial clef ting. In additon, genetic studies in Japanese are limited; thus, future work is awaited.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 47 (8), 521-527, 2001
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001206528073600
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- NII論文ID
- 10009460544
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可