多発性筋炎に合併した早期食道癌の１例

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  • A Case of Early Esophageal Carcinoma with Polymyositis.

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A rare case of early esophageal cancer associated with polymyositis is presented. A 73-year-old man was referred to the hospital because of bilateral edema and arthralgia of the hands in October 2000. The patient was diagnosed with polymyositis by: musle weakness of the extremities; elevated levels of creative kinase, transaminase, LDH, aldolase and myoglobin on blood chemistry; electromyogram; and muscle biopsy. Endoscopic examination to screen for possible malignancy disclosed squamous cell carcinoma in the lower thoracic esophagus. Elevated levels of creatine kinase, transaminase, LDH, aldolase and myoglobin were normalized and muscle weakness resolved following treatment with 50mg/day of prednisolone. Partial esophagectomy was performed with gastric reconstruction via a posteriormediastinal approach. Macroscopically a 0-IIc type tumor measuring 1.2 ×1.5cm was observed in the lower thoracic esophagus. Pathological examination of the resected specimen revealed well differentiated squamous cell carcinoma, ly 0 , v 0 , INFβ, ow(-), aw(-), pT1b, pN0, pM0 and pStage I. As of 10 months after the resection of the esophageal cancer, polymyositis remains relieved and no recurrence of cancerhas occurred.

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