術後肝転移に対し肝動注化学療法が奏効した食道の“いわゆる癌肉腫”の1例

  • 高谷 義博
    自治医科大学附属大宮医療センター消化器・一般外科
  • 清崎 浩一
    自治医科大学附属大宮医療センター消化器・一般外科
  • 宮田 道夫
    自治医科大学附属大宮医療センター消化器・一般外科
  • 小西 文雄
    自治医科大学附属大宮医療センター消化器・一般外科

書誌事項

タイトル別名
  • Transcatheter Arterial Infusion Chemotherapy Against the Liver Metastasis from So-called Esophageal Carcinosarcoma. A Case Report.

この論文をさがす

抄録

A 62-year-old woman admitted for dysphasia was found in esophagography and esophagoscopy to have a pedunculated polypoid tumor 30cm from an incisor. Biopsy revealed carcinosarcoma, necessitating subtotal esophagectomy with 3-field lymphadenectomy. On gross appearance, the tumor showed an unclassifiable appearance, type 5s. It consisted of 2 types of malignant lesion bordered by a transient zone histologically. One lesion was sarcoma stained immunohistochemically with HHF 35, vimentin, and a-smooth muscle actin, and the other squamous cell carcinoma positive to type 1 cytokeratin. Based on this evidence, we concluded this tumor to be so-called carcinosarcoma. Histologically, paratracheal and posterior mediastinal lymphnodes included malignant cells and adjuvant chemotherapy (5-FU and CDDP) was conducted following surgical exploration. One year later, a metastatic lesion was recognized in the lateral segment of the liver in computed tomography. A transhepatic arterial injection of CDDP 50mg on day 1 and intravenous infusion of 5-FU 1, 000mg on days 1 to 5 was repeated 3 times in 6 months because surgery would injure the reconstructed gastric tube. The metastatic lesion disappeared completely after chemotherapy. Multiple recurrent lesions appeared in the liver 12 months later after the complete response, eventually leading to her death of cancer. Few reports have been made on chemotherapy for such liver metastasis. <br> Guidelines of the Japanese Society for Esophageal Diseases

収録刊行物

被引用文献 (4)*注記

もっと見る

参考文献 (12)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ