Annual changes in susceptibility of clinical isolates to biapenem.

• Hirakata Yoichi

  Second Department of Internal Medicine, Nagasaki University School of Medicine Department of Laboratory Medicine, Nagasaki University School of Medicine

• Matsuda Junichi

  Department of Laboratory Medicine, Nagasaki University School of Medicine

• Mochida Chikako

  Department of Laboratory Medicine, Nagasaki University School of Medicine

• Nakano Michiko

  Department of Laboratory Medicine, Nagasaki University School of Medicine

• Hirayama Mitsukuni

  Department of Laboratory Medicine, Nagasaki University School of Medicine

• Iori Fumiaki

  Department of Laboratory Medicine, Nagasaki University School of Medicine

• Kamihira Shimeru

  Department of Laboratory Medicine, Nagasaki University School of Medicine

• Tomono Kazunori

  Second Department of Internal Medicine, Nagasaki University School of Medicine

• Yanagihara Katsunori

  Second Department of Internal Medicine, Nagasaki University School of Medicine

• Miyazaki Yoshitugu

  Second Department of Internal Medicine, Nagasaki University School of Medicine

• Kadota Junichi

  Second Department of Internal Medicine, Nagasaki University School of Medicine

• Hara Kohei

  Second Department of Internal Medicine, Nagasaki University School of Medicine

• Kohno Shigeru

  Second Department of Internal Medicine, Nagasaki University School of Medicine

Bibliographic Information

Other Title

• Ｂｉａｐｅｎｅｍに対する各種臨床分離菌株の薬剤感受性の年次推移について

Abstract

Annual changes in susceptibility of biapenem (BIPM), a new injectable carbapenem, against 1, 032clinical strains (14 species) including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Pseudomonas aeruginosa, etc., were determined by agar dilution. Strains were isolated from patients in the Nagasaki University Hospital from January 1994 to December 1996. Comparison of annual changes of MIC₅₀ and MIC₉₀ against S. aureus including methicillin-resistant strains, S. pneumoniae including penicillin-resistant strains, Streptococcus pyogenes, Enterococcus faecalis, E. coli, Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis, Acinetobacter baumannii, and Moraxella catarrhalis did not show increased resistance. Staphylococcus epidermidis and Serratia marcescens showed a slight increase in carbapenem-resistant strains, judging from MIC₅₀. Although P. aeruginosa also showed an increase in carbapenem-resistant strains by the comparison of MIC₉₀, the tendency toward BIPM resistance against this species was lower than those of other carbapenems. Among Haemophilus influenzae isolated in 1996, some strains were resistant strains toβ-lactams including carbapenems, so we must note this tendency.

Journal

• Japanese Journal of Chemotherapy

  Japanese Journal of Chemotherapy 50 (6), 329-351, 2002

  Japanese Society of Chemotherapy

Keywords

• biapenem

Details

• CRID: 1390001206284992512
• NII Article ID: 10009512926
• NII Book ID: AN10472127
• DOI: 10.11250/chemotherapy1995.50.329
• ISSN: 18845886
• ISSN: 13407007
• HANDLE: 10069/26660
• Web Site: https://nagasaki-u.repo.nii.ac.jp/records/12495
• Web Site: https://search.jamas.or.jp/link/ui/2003008920
• Text Lang: ja
• Data Source:
  • JaLC
  • IRDB
  • CiNii Articles
• Abstract License Flag: Disallowed