Effect of Quinoa on Blood Pressure and Lipid Metabolism in Diet-induced Hyperlipidemic Spontaneously Hypertensive Rats (SHR).

• Ogawa Hiroshi

  Department of Hygiene, Kinki University School of Medicine

• Watanabe Katsumi

  Department of Food Science and Nutrition, Faculty of Agriculture, Kinki University

• Mitsunaga Toshio

  Department of Food Science and Nutrition, Faculty of Agriculture, Kinki University

• Meguro Tadamichi

  Department of Hygiene, Kinki University School of Medicine

Bibliographic Information

Other Title

• キノア投与が食餌性高脂血症誘導高血圧自然発症ラット（ＳＨＲ）の血圧，脂質代謝に及ぼす影響
• キノア トウヨ ガ ショクジセイ コウシケツショウ ユウドウ コウケツアツ シゼン ハッショウ ラット SHR ノ ケツアツ シシツ タイシャ ニ オヨボス エイキョウ

Abstract

It is well documented that the quality of quinoa (Chenopodium quinoa) protein matches that of milk casein, and quinoa abundantly contains several micronutrients such as potassium, iron, calcium and riboflavin. In this study, we investigated the functional properties of quinoa (dehulled quinoa flour), using spontaneously hypertensive rats (SHR) with hyperlipidemia induced by a high-lipid diet. Groups of 6 male rats, 11 weeks of age, were used. An experimental group was fed the quinoa diet whose components were adjusted to those of a high-lipid casein diet (control) for 6 weeks. Although significant decreases in food intake and growth rate were observed in the experimental group during the first two weeks, such differences were not recognized after two weeks. The increase in systolic blood pressure in the experimental group was significantly suppressed at 5 weeks of feeding, suggesting that quinoa had a hypotensive effect. In addition, the serum apolipoprotein (apo) A-I concentration was significantly high, and the apoB/apoA-I ratio significantly low, compared with those in the control group. The relative weight of the liver was significantly low in the experimental group, while no significant differences were observed in the lipid content and enzyme activities related to cholesterol metabolism.

Journal

• Nippon Eiyo Shokuryo Gakkaishi

  Nippon Eiyo Shokuryo Gakkaishi 54 (4), 221-227, 2001

  Japan Society of Nutrition and Food Science

Keywords

• quinoa flour
• SHR
• blood pressure
• lipid metabolism
• apolipoproteins

Details

• CRID: 1390282681269700864
• NII Article ID: 10009715285
• NII Article ID: 10008560199
• NII Book ID: AN00311992
• DOI: 10.4327/jsnfs.54.221
• COI: 1:CAS:528:DC%2BD3MXmsVGqsbk%3D
• ISSN: 18832849
• ISSN: 02873516
• ISSN: http://id.crossref.org/issn/02873516
• NDL BIB ID: 5869828
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5869828
• Web Site: https://search.jamas.or.jp/link/ui/2002031664
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed