植物ステロール／スタノールの血中コレステロール低下効果　　最少有効摂取量について

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タイトル別名
  • Effect of Plant Sterols and Stanols on Blood Cholesterol Level: Clinical Evidence of Minimum Effective Dose.
  • ショクブツ ステロール スタノール ノ ケッチュウ コレステロール テイカ コウカ サイショウ ユウコウ セッシュリョウ ニ ツイテ
  • Clinical Evidence of Minimum Effective Dose
  • 最少有効摂取量について

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Plant sterols, which have chemical structures similar to cholesterol, are abundant in the fat-soluble fraction of plants. Plant sterols have been shown to reduce the concentration of plasma total- and low-density-lipoprotein (LDL) -cholesterol in a series of clinical trials. Their hypocholesterolemic effect is exerted through the inhibition of cholesterol absorption in the intestinal lumen. Plant stanols are saturated derivatives of plant sterols. Although several studies have reported that plant stanols have a greater cholesterol-lowering activity than plant sterols, others have failed to observe any difference between the effects of these two compounds. Through investigation of various clinical studies, the least effective dose of plant sterols and stanols is estimated to be 0.8g/day.

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