甜茶（ｒｕｂｕｓ　ｓｕａｖｉｓｓｉｍｕｓ）熱水抽出エキスの抗アレルギー作用

• 石倉 義之

  サントリー株式会社基礎研究所

• 諏訪 芳秀

  サントリー株式会社基礎研究所

• 岡田 力

  サントリー株式会社生物医学研究所

• 河野 茂勝

  京都薬科大学薬理学教室

書誌事項

タイトル別名

• Anti-allergic effects of rubus suavissimus extract.

抄録

Rubus suavissimus is a kind of the plants in Rosaceae, the leaves of which have been brewed and drunk as a usual drink in China. It has been experientially known that the tea is effective for sore throat and laryngitis.<BR>In the present experiments, we investigated the influence of the Rubus suavissimus extracts on experimental allergy. As the results, the extracts showed the suppressive effects on cyclooxygenase activity and anaphylactically induced histamine release from rats peritoneal mast cells, in vitro. In addition to these, oral administration of the extracts significantly inhibited either skin reaction induced by compound 48/80 or passive cutaneous anaphylaxis in the rat.<BR>These results suggest that the rubus suavissimus extracts are therapeutically effective for inflammatory and allergic diseases.

収録刊行物

• 炎症

  炎症 15 (2), 167-173, 1995

  日本炎症・再生医学会

キーワード

• <I>rubus suavissimus</I>
• <I>mast cell</I>
• <I>histamine</I>
• <I>vascular permeability</I>
• <I>PCA</I>

詳細情報

• CRID: 1390001204783951616
• NII論文ID: 130003856418
• NII論文ID: 10009774232
• NII書誌ID: AN00357213
• DOI: 10.2492/jsir1981.15.167
• ISSN: 18844006
• ISSN: 03894290
• ISSN: http://id.crossref.org/issn/03894290
• Web Site: https://search.jamas.or.jp/link/ui/1996104224
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可