A CASE OF MALIGNANT PHYLLODES TUMOR ASSOCIATED WITH NON-INVASIVE DUCTAL CARCINOMA OF THE BREAST

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  • 乳腺悪性葉状腫瘍に非浸潤性乳管癌を合併した1例

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Abstract

We experienced a case of malignant phyllodes tumor associated with non-invasive ductal carcinoma of the breast.<br> A 51-year-old woman was seen at the hospital because of a left breast mass. At the first visit, a 3×3cm elastic hard tumor extending from the C to D areas was palpated. A needle biopsy cytology offered a diagnosis of benign phyllodes tumor and the patient was decided to be followed on an ambulant basis. About 6 months later, the tumor began to enlarge rapidly and then it was extirpated under general anesthesia. Histopathological exploration revealed that the tumor was phyllodes tumor with malignant picture and several ductal structures which should be called intraductal carcinoma adjacent to the phyllodes tumor. The definite diagnosis of non-invasive ductal carcinoma with malignant phyllodes tumor was made.<br> It is extremely rare that phyllodes tumor is associated with breast cancer and reported cases have numbered only 20 in Japan so far. Of these 20 cases, 13 cases were of ipsilateral and synchronous like this case, five cases were of contralateral and synchronous, and two cases were of ipsilateral and metachronous.

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