ポーリング処理されたアパタイトが示す骨形成能の活性化

• 小林 孝之

  アニマルクリニックこばやし 東京医科歯科大学生体材料工学研究所素材部門無機材料分野

• 中村 聡

  東京医科歯科大学生体材料工学研究所素材部門無機材料分野

• 山下 仁大

  東京医科歯科大学生体材料工学研究所素材部門無機材料分野

書誌事項

タイトル別名

• Activation of New Bone Formability with Polarized Hydroxyapatite.
• ポーリング ショリ サレタ アパタイト ガ シメス ホネ ケイセイノウ ノ カッセイカ

抄録

Acceleration and deceleration of bone like crystal and bone formation of electrically polarized hydroxyapatite (HA) ceramics were demonstrated by in vitro and in vivo evaluations. The electrical polarizability and large induced surface charge of HA were proved by ther-mally stimulated current measurements (TSDC) . Cultured osteoblastic cells were found to be activated on the overgrown bone-like HA layers on the negatively charged surfaces while the cells directly placed on the positively charged surfaces were lower proliferated. The negatively charged HA surface exhibited the enhanced osteogenesis with direct bone contacting in early stage of rabbit tibial and femoral implantations. The positively charged surface resulted in a small amount of bone formation on the ceramic surface. On the contrary in the zone isolated by a fibrous layer, a large volume of bones newly formed. In orthopedic and dental fields, it is useful that the outstanding bone-formability in early stage on the negatively charged surface conducts more rigid initial fixation. The positive surface charges show the new bone conducting property affecting over a long distance and have the possibility of controlling osteogesis.

収録刊行物

• 獣医麻酔外科学雑誌

  獣医麻酔外科学雑誌 32 (3/4), 55-66, 2001

  獣医麻酔外科学会

キーワード

• 電気分極
• 水酸アパタイト
• 骨形成
• 表面電荷

詳細情報

• CRID: 1390001204720645248
• NII論文ID: 130004184953
• NII論文ID: 10009936938
• NII書誌ID: AN10158155
• DOI: 10.2327/jvas.32.55
• ISSN: 13497669
• ISSN: 09165908
• NDL書誌ID: 6044869
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6044869
• Web Site: https://search.jamas.or.jp/link/ui/2002173250
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可