胆嚢小細胞癌・下部胆管腺癌の同時性重複癌の1例

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  • A Case of Synchronous Double Cancer Comprising Small Cell Carcinoma in the Gallbladder and Adenocarcinoma in the Common Bile Duct.

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We report a case of synchronous double cancer comprising adenocarcinoma in the common bile duct and small cell carcinoma in the gallbladder. A 60-year-old man admitted to our hospital with because of fever and abdominal pain was diagnosed with having common bile duct cancer. A pancreatoduodenectomy was carried out in November 2001. Postoperative examination of the resected specimens disclosed another 25×20 mm tumorous lesion in the gallbladder, in addition to the tumor of the common bile duct. Histological examination showed well differentiated adenocarcinoma of the common bile duct and small cell carcinoma of the gallbladder. Postoperatively, the patient was treated by adjuvant chemotherapy with CPT-11+CDDP. He is alive without recurrence. In fact, small cell carcinoma of the gallbladder is extremely uncommon and difficult to treat. Survival analysis of this disease supported the efficacy of the combination therapy in comparison to surgery alone. However, to our knowledge, this is the first case of treatment with CPT-11 for small cell carcinoma of the gallbladder.

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