ＨＴＬＶ‐Ｉウイルス関連リンパ節炎

• 大島 孝一

  福岡大学医学部第一病理

• 菊池 昌弘

  福岡大学医学部第一病理

書誌事項

タイトル別名

• HTLV-I associated lymphadenitis.

抄録

We examined the histopathologic changes of lymph nodes from 10 patients with mild lymphadenopathy, a few atypical lymphocytes in peripheral blood, skin lesions, and proviral DNA of human T-cell leukemia virus type I (HTLV-I) in the nodes. The proviral DNA of HTLV-I was detected by Southern blot analysis, in situ hybridization technique, and/or polymerase chain reaction. The lymph nodes showed preserved nodal architecture with diffuse infiltration of small to intermediate sized lymphocytes in association with scattered transformed lymphocytes and few immunoblast-like cells in the enlarged paracortex. The infiltrating lymphocytes were positive for CD4, but neither rearrangement nor deletion of T-cell receptors and immunoglobulin heavy chain genes was detected. All patients were alive and healthy at more than 5 months after the biopsies. The histology resembled that of a viral infection and could be distinguished from HTLV-I associated lymphomas.

収録刊行物

• 日本リンパ網内系学会会誌

  日本リンパ網内系学会会誌 39 (1), 27-32, 1999

  日本リンパ網内系学会

キーワード

• HTLV-I
• Lymphadenitis
• CD4

詳細情報

• CRID: 1390282679679210624
• NII論文ID: 10010347553
• NII書誌ID: AA11131108
• DOI: 10.3960/jslrt1997.39.27
• ISSN: 1883681X
• ISSN: 13429248
• Web Site: https://search.jamas.or.jp/link/ui/1999178782
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可