ウイルス性急性肝炎および劇症肝炎の末梢血リンパ球Ｔｈ１／Ｔｈ２バランス

• 小野寺 誠

  岩手医科大学第1内科

• 遠藤 龍人

  岩手医科大学第1内科

• 阿部 弘一

  岩手医科大学第1内科

• 滝川 康裕

  岩手医科大学第1内科

書誌事項

タイトル別名

• Th 1/Th 2 balance of peripheral T helper cells in acute viral hepatitis and fulminant hepatitis.

抄録

To elucidate the cause of the severe state in acute viral hepatitis, the Th1/Th2 balance of peripheral CD4+ T cells was analyzed in acute viral hepatitis and in fulminant hepatitis. The study populations consisted of patients with acute viral hepatitis (AH n=17), the severe from of acute viral hepatitis (AHS n=9), fulminant hepatitis (FH n=9), and controls (n=35). The number of Th1 cells, Th2 cells, and the ratio of Th1/Th2 were measured using flow cytometry. IL-18 levels were measured using an ELISA kit and their correlation to Th1 cells, Th2 cells, and the ratio of Th1/Th2 was investigated. Th1 levels were significantly lower in FH than in AH (p<0.01). The values measured for FH tended to be lower than those measured for AH and AHS. The level of IL-18 was high in AH, AHS, and FH, but was not correlated with Th1/Th2.

収録刊行物

• 肝臓

  肝臓 43 (12), 550-558, 2002

  一般社団法人　日本肝臓学会

キーワード

• Th1/Th2バランス
• ウイルス性肝炎
• 劇症肝炎

詳細情報

• CRID: 1390001204790576512
• NII論文ID: 10010568693
• NII書誌ID: AN00047770
• DOI: 10.2957/kanzo.43.550
• ISSN: 18813593
• ISSN: 04514203
• Web Site: http://www.jstage.jst.go.jp/article/kanzo1960/43/12/43_12_550/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2003179671
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可