13歳女児にみられたニフェジピンによる歯肉増殖症の1例

• 佐野 富子

  新潟大学歯学部小児歯科学講座

• 富沢 美惠子

  新潟大学歯学部小児歯科学講座

• 朔 敬

  新潟大学歯学部口腔病理学講座

書誌事項

タイトル別名

• Gingival Hyperplasia Induced by Nifedipine in a 13-year-old Girl: Report of a Case

抄録

Nifedipine, a calcium antagonist, is commonly prescribed medication for hypertension and angina pectoris. Many clinical cases of gingival hyperplasia associated with nifedipine therapy have been reported since 1984, when Ramon et al reported the first case. Child cases have however been rarely documented. We report a case of gingival hyperplasia induced by nifedipine administration in a 13year-old girl. Oral examination showed marked gingival hyperplasia around the interdental papillae of the upper and lower incisors. The affected gingiva were nodular and elastically hard. Since the patient had received nifedipine for 9 months for treatment of renal hypertension, we suspected side-effects caused by the nifedipine and consulted her pediatrician about a change in the patient's medication. Since the hyperplastic gingiva did not improve in spite of a gradual reduction of the dose of nifedipine, plaque control and scaling, we performed gingivectomy under local anesthesia. There have not been any signs of recurrence during the following 11 months of observation. Histopathologically, drug-induced gingival hyperplasia was confirmed. This is the first case report of Nifedipine-induced gingival hyperplasia in a child.

収録刊行物

• The Japanese Journal of Pediatric Dentistry

  The Japanese Journal of Pediatric Dentistry 37 (4), 864-870, 1999

  The Japanese Society of Pediatric Dentistry

キーワード

• 歯肉増殖症
• カルシウム拮抗剤
• ニフェジピン
• 副作用
• 小児

詳細情報

• CRID: 1390282679659269248
• NII論文ID: 130004633765
• NII論文ID: 10010635919
• NII書誌ID: AN00116228
• DOI: 10.11411/jspd1963.37.4_864
• ISSN: 05831199
• Web Site: https://search.jamas.or.jp/link/ui/2000104762
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可