橋深部小梗塞の発症機序の検討―MRI拡散強調画像を用いた解析―

書誌事項

タイトル別名
  • Etiological mechanisms of acute pontine infarction
  • MRI拡散強調画像を用いた解析

この論文をさがす

抄録

The purpose of the present study was to clarify the etiological mechanisms of small pontine infarctions using diffusion-weighted magnetic resonance imaging (DWI). We investigated 26 consecutive patients with acute pontine infarctions of which the lesions were localized within the pons on DWI performed within 7 days after the onset. DWI revealed pontine infarctions extending to the basal surface in 15 patients (group 1) and deep pontine infarctions without extension to the basal surface in 10 patients (group 2). One patient whose DWI showed two pontine infarctions (one extended to the basal surface and the other did not) was excluded from subsequent analysis. Multiple extrapontine high intensity regions were observed in one patient of group 1 (hemodynamic infarction) and in 5 patients of group 2 (embolic infarctions), the difference being statistically significant (p=0.02). The patients' background, clinical course and MR angiography findings were compared between the two groups. Diabetes mellitus, fluctuations or progression of neurologic deficits during the acute stage and intracranial arterial stenosis were more frequently observed in group 1 than in group 2. These findings suggest that the etiological mechanism of pontine infarction in group 1 probably involved large-vessel disease or branch atheromatous disease, while that in group 2 appeared to be embolic (artery-to-artery or cardioembolic) or due to hypertensive small-vessel disease.

収録刊行物

  • 脳卒中

    脳卒中 24 (2), 216-222, 2002

    一般社団法人 日本脳卒中学会

被引用文献 (2)*注記

もっと見る

参考文献 (26)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ