リン酸四カルシウムを基剤とした根管充填剤の根尖周囲組織反応について

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  • Periapical Tissure Reactions in Dogs to Root Canal Fillings Containing Tetracalcium Phosphate

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The biocompatibilities of new root canal fillings, CPO and CPE, composed of tetracalcium phosphate (4 CP) powder with either oleic acid or eugenol, respectively, were examined histopathologically and radiographically in 12 dogs. The root canals of 14 teeth per dog were filled with CPO, CPE or zinc oxide-eugenol (ZOE) and the periapical tissue reactions were evaluated 1,4,8,12 weeks after filling. Hard tissue formation was observed around CPO and CPE. Furthermore, the periapical tissue exposed to CPO revealed slight or moderate inflammation throughout the experimental periods, while severe inflammation was found in the periapical tissue around CPE. These findings suggest the usefulness of CPO as a root canal filling.

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