ハンセン病の病理：　ハンセン病と腎病変

• 松尾 英一

  杏林大学医学部第1病理学教室

• 古野 之洋

  杏林大学医学部第1病理学教室

• 小松 明男

  杏林大学医学部第1病理学教室

• 前川 傑

  杏林大学医学部第1病理学教室

• 村田 建一郎

  杏林大学医学部第1病理学教室

• Sidik Hamit

  Department of Pathology Kyorin University School of Medicine

• 菊池 太陽

  杏林大学医学部第1病理学教室

• 佐々木 紀典

  老人保養施設•グリーンボイス

書誌事項

タイトル別名

• Hansen's Disease and Nephropathy As Its Sequence.

抄録

Nephropathy as the sequences of Hansen's disease before and after the introduction of chemotherapy was compared referring to the report by Hayashi in 1943 and the summary of the autopsy reports from 1978 to 1981 at National Hansen's disease hospital Zenseien.<br>Unlike the high rates of tuberculosis as the cause of death before the introduction of chemotherapy (41.3%) those thereafter decreased to be negligible. On the other hand the comparison of the rates of nephropathy with the same way as that of tuberculosis was impossible since the description about nephropathy by Hayashi was not sufficient to characterize each nephropathy since he included arteriolitis, glomerulonephritis and interstitial nephritis together in the term of nephritis. Death rate due to nephritis among Hansen's disease patients according to Hayashi at that time was 21.2% which was twice as many comparing to that in the other cases. According to the report about the cases of Zenseien those reported to have glomerulonephritis was 37.3% though those were not necessarily listed as the cause of death. Also the nephropathy including fibrinoid angitis with occasional microaneurysmal dilatation of afferent arteries, glomerulitis, sclerosis and stricture of efferent arteries likewise ischemic acute tubular necrosis possibly as the result of these angiopathy seemed to be present. These vascuar changes partially resemble to that of microscopic periarteritis nodosa but seems to be common in the smaller arteries.<br>In conclusion, unlike the case of tuberculosis the rate of nephritis including glomerilitis, arteriolitis and interstitial nephritis as Hayashi used as his criteria does not seem to have decreased. Therefore, the critical analysis of the nephropathy especially of that relating to the arteriolitis should be done to obtain the knowledge to suppress its occurence.

収録刊行物

• 日本ハンセン病学会雑誌

  日本ハンセン病学会雑誌 66 (2), 103-108, 1997

  日本ハンセン病学会

キーワード

• ハンセン病
• 結核
• 反応
• 血管炎
• 腎炎

詳細情報

• CRID: 1390282681297864448
• NII論文ID: 10011181982
• NII書誌ID: AN10559906
• DOI: 10.5025/hansen.66.103
• ISSN: 1884314X
• ISSN: 13423681
• PubMed: 9301209
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可