下顎に転移した腫よう7例の検討

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  • Metastatic mandibular tumor: Report of 7 cases.

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Seven patients with metastatic mandibular tumors are described. The primary tumors in these patients included papillary carcinoma of the thyroid gland, adenocarcinoma of the lung, large cell carcinoma of the lung, osteosarcoma of the tibia, adenocarcinoma of the stomach, neuroepithelioma of the lumbar dura, and adenocarcinoma of the colon. Five patients were older than 60 years of age and 2 were younger than 20 years. In 5 patients metastatic mandibular tumors were confirmed histologically, and in 2 patients metastasis to the mandible was diagnosed radiologically and clinically. Four tumors had metastasis to the mandibular gingiva and 3 had metastasis to the mandibular bone.<BR>Teeth and inflammation of the gingiva were considered to have crucial effects on the development of gingival metastasis. The most common symptoms of gingival metastasis were gingival lumps and swellings resembling an epulis and periodontitis.<BR>Mandibular bone metastasis was noted in the ramus of the mandible. The most common symptoms of mandibular bone metastasis were pain of the mandible and paresthesia of the mental nerve.<BR>Surgical removal was indicated for the metastatic gingival tumors and radiotherapy was the treatment of choice for the mandibular bone metastasis.<BR>The outcome of the patients with metastatic mandibular tumors was very poor: 6 patients died within 6 months, and 1 patient died 7 years and 2 months after treatment.<BR>As the treatment of metastatic mandibular tumors generally carries a poor prognosis, the patient's quality of life (QOL) should be considered when planning treatment.

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