閉塞型睡眠時無呼吸と肥満についての検討―肥満と体重増加度―

  • 釼持 睦
    聖マリアンナ医科大学横浜市西部病院耳鼻咽喉科
  • 佐藤 成樹
    聖マリアンナ医科大学横浜市西部病院耳鼻咽喉科
  • 宮本 康裕
    聖マリアンナ医科大学横浜市西部病院耳鼻咽喉科
  • 杉田 明美
    聖マリアンナ医科大学横浜市西部病院耳鼻咽喉科
  • 田中 泰彦
    聖マリアンナ医科大学耳鼻咽喉科学教室
  • 大橋 徹
    秦野赤十字病院耳鼻咽喉科
  • 肥塚 泉
    聖マリアンナ医科大学耳鼻咽喉科学教室

書誌事項

タイトル別名
  • Examination of the Relationship between OSA and Obesity
  • ヘイソクガタ スイミンジ ムコキュウ ト ヒマン ニ ツイテ ノ ケントウ ヒマン ト タイジュウ ゾウカド
  • 肥満と体重増加度

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抄録

Obesity is one of most important risk factors for obstructive sleep apnea syndrome (OSA). In this studys, we examined the importance of a rapid and considerable increase in body weight in OSA using a weight changing index (WCI). We investigated 39 patients (35 males and 4 females) that were referred to our hospital complaining of snoring and sleeping disturbance, and we employed body mass index (BMI) to evaluate obesity. The BMI was estimated as body weight divided by height to the second power: BMI (kg/m2)=body weight/(height * height). WCI was estimated as the previous BMI around the time the patients noticed sleeping disturbance, minus the present BMI. We evaluated degrees of OSA using the apnea-hypopnea index (AHI) as measured by polysomnography. We found a significant correlation between AHI and BMI, confirming that obesity greatly influences OSA. In younger subjects, the correlation between OSA and increases in WCI was more prominent than that in older subjects, whereas the BMI values did not differ significantly with age. Since WCI appeared to reflect the accumulation of visceral fat, we suggest that visceral-fat obesity most strongly influences OSA. The increasing prevalence of obesity is likely to produce social problems associated with a higher incidence of OSA. It is therefore important to develop suitable methods for the detection and treatment of OSA.

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