胆嚢未分化癌の１例

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  • A CASE OF THE UNDIFFERENTIATED CARCINOMA ARISEN IN THE GALLBLADDER

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A 69-year-old man who had been followed for a polyp of the gallbladder detected in November 1998 at another hospital was found to have anemia, and was referred to the hospital. Abdominal CT scan visualized a tumor shadow about 3.5 cm in diameter at the fundus of gallbladder, and a tumor shadow about 2 cm in diameter in the hepatoduodenal mesentery suggestive of lymph node metastasis. Abdominal angiography showed accumulation of contrast material at the periphery of the gallbladder artery. With a diagnosis of the gallbladder cancer, an extended cholecystectomy, excision of the extrahepatic bile duct and D2 lymph node dissection were performed on January 25, 2001. On the surgical stump of the excised material, the tumor was 4.0×4.3 cm in diameter and the section was yellowish white in color and solid. Histopathologically anhistic arrangement of large tumor cells with relatively wide cytoplasm and prominent atypical nuclei was observed. On immunostainings, undifferentiated carcinoma originated from the gallbladder was diagnosed.<br>It is believed that undifferentiated carcinoma of the gallbladder is relatively rare, and this rare case is presented here, together with some bibliographical comments.

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