タンパク質研究の最先端 : 構造ゲノミクス Structural Genomics, Leading the Van of Protein Science

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抄録

In the post-genome sequencing era, "Structural Genomics" has become one of the most important research fields in life science. Here I introduce the outline of the study of structural genomics in RIKEN Genomic Sciences Center and also the connection between surface science and structural genomics. Structural genomics is an emerging research field, which examines the enormous amounts of information stored in the genomes of living organisms. We are trying to determine a variety of three-dimensional structures of protein mainly by NMR and also to analyze the structure-function relationship of the proteins systematically and comprehensively. In the process of protein function analysis, molecular interaction analysis is very important and we use various methods including <I>in silico</I> screening, mass spectrometry, surface plasmon resonance, NMR, and so on. All of these analytical methods are based on protein-ligand interaction on molecular surfaces.

収録刊行物

  • 表面科学 : hyomen kagaku = Journal of the Surface Science Society of Japan

    表面科学 : hyomen kagaku = Journal of the Surface Science Society of Japan 24(11), 689-693, 2003-11-10

    The Surface Science Society of Japan

参考文献:  8件中 1-8件 を表示

  • <no title>

    廣田洋

    実験医学 18, 1722, 2000

    被引用文献1件

  • <no title>

    廣田洋

    ゲノム創薬の新潮流 127, 2000

    被引用文献1件

  • <no title>

    廣田洋

    medical forum CHUGAI 6, 2, 2002

    被引用文献1件

  • <no title>

    SERVICE R. F.

    Science 298, 948, 2002

    被引用文献4件

  • <no title>

    YOKOYAMA S.

    Nature Struct. Biol. 7, 943, 2000

    被引用文献3件

  • <no title>

    廣田洋

    実験医学 19, 958, 2001

    被引用文献1件

  • <no title>

    廣田洋

    特開 2003-248001

    被引用文献1件

  • <no title>

    FURUKAWA H.

    Mol. Pharm. 62, 778, 2002

    被引用文献1件

各種コード

  • NII論文ID(NAID)
    10012433757
  • NII書誌ID(NCID)
    AN00334149
  • 本文言語コード
    JPN
  • 資料種別
    REV
  • ISSN
    03885321
  • データ提供元
    CJP書誌  J-STAGE 
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