Modification of mercury toxicity by selenium: proctical importance?
-
- WATANABE CHIHO
- Department of Human Ecology, Graduate School of Medicine, University of Tokyo
書誌事項
- タイトル別名
-
- Modification of Mercury Toxicity by Selenium: Practical Importanc?
この論文をさがす
抄録
The interaction between mercury and selenium may involve a variety of toxicologically and biochemically distinct processes. In this paper, the interaction between inorganic mercury and sodium selenite, the interaction most extensively studied, as well as the interaction between methylmercury (MeHg) and selenium, the interaction perhaps most significant for non-occupational human populations, will be discussed. It has been shown that the former interaction can be understood as a modification of the kinetic behavior of inorganic mercury by selenite, but this interaction may occur only under very limited conditions. On the other hand, the mechanism of the latter interaction is largely unknown, and kinetic modification appears to play only a minor role. An interaction between MeHg and selenoproteins or a possible interaction between the inorganic mercury, resulting from the demethylation of MeHg, and the selenium may be important. Compared to the experimental findings, little evidence of the toxicological modification of MeHg by selenium was obtained in epidemiological studies.
収録刊行物
-
- The Tohoku Journal of Experimental Medicine
-
The Tohoku Journal of Experimental Medicine 196 (2), 71-77, 2002
東北ジャーナル刊行会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679218694400
-
- NII論文ID
- 10012575278
-
- NII書誌ID
- AA00863920
-
- COI
- 1:CAS:528:DC%2BD38XjtlClsLw%3D
-
- ISSN
- 13493329
- 00408727
-
- PubMed
- 12498318
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可