Fabrication of Ultrathin, Protein-containing Films by Layer-by-Layer Assembly and Electrochemical Characterization of Hemoglobin Entrapped in the Film

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著者

    • SHANG Libin
    • Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University
    • LIU Xinjian
    • Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University
    • ZHONG Jun
    • Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University
    • FAN Chunhai
    • Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University
    • LI Genxi
    • Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University

抄録

Multilayers of hemoglobin were uniformly deposited on a pyrolytic graphite electrode surface through a layer-by-layer self-assembly approach. The well-known anionic polyelectrolyte, DNA, was used to attract cationic hemoglobin due to the strong electrostatic interaction between DNA and the protein. Interestingly, the electron transfer reactivity of hemoglobin was significantly improved in the film, which in turn facilitated the electrocatalytic reduction of nitric oxide.

収録刊行物

  • Chemistry letters

    Chemistry letters 32(3), 296-297, 2003-03-05

    The Chemical Society of Japan

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各種コード

  • NII論文ID(NAID)
    10012815108
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    03667022
  • データ提供元
    CJP書誌  J-STAGE 
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