構造グライコミクスの役割 Mission of Structural Glycomics

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著者

    • 平林 淳 HIRABAYASHI Jun
    • 独立行政法人産業技術総合研究所糖鎖工学研究センター糖鎖構造解析チーム Glycostructure Analysis Team, Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology

抄録

"Functional glycomics"is a coming area of glycoscience and glycotechnology, which aims at elucidating biological roles of protein glycosylation from a holistic viewpoint, in a particular context of post-genomics and post-proteomics. However, analysis of glycans, i.e., the third bio-informative chain, should meet various difficulties due to many factors which other bio-macromolecules lack, e.g., branching and linkage isomerism. Recently, unique methods, which enable a large scale of identification methods of glycoproteins have been developed independently in two groups. In this chapter, advanced methods for glycoproteomics enabling identification of both core proteins and glycosylation sites are described as well as subsequent glycan profiling by means of lectin-affinity technologies.

収録刊行物

  • 生物物理化学 = Journal of Electrophoresis

    生物物理化学 = Journal of Electrophoresis 48(1), 11-17, 2004-03-15

    Japanese Electrophoresis Society

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各種コード

  • NII論文ID(NAID)
    10012842261
  • NII書誌ID(NCID)
    AN00129729
  • 本文言語コード
    JPN
  • 資料種別
    REV
  • ISSN
    00319082
  • NDL 記事登録ID
    6894420
  • NDL 雑誌分類
    ZR2(科学技術--生物学--生化学)
  • NDL 請求記号
    Z18-127
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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