Mission of Structural Glycomics.

• Hirabayashi Jun

  Glycostructure Analysis Team, Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology

Bibliographic Information

Other Title

• 構造グライコミクスの役割
• コウゾウ グライコミクス ノ ヤクワリ

Abstract

“Functional glycomics”is a coming area of glycoscience and glycotechnology, which aims at elucidating biological roles of protein glycosylation from a holistic viewpoint, in a particular context of post-genomics and post-proteomics. However, analysis of glycans, i.e., the third bio-informative chain, should meet various difficulties due to many factors which other bio-macromolecules lack, e.g., branching and linkage isomerism. Recently, unique methods, which enable a large scale of identification methods of glycoproteins have been developed independently in two groups. In this chapter, advanced methods for glycoproteomics enabling identification of both core proteins and glycosylation sites are described as well as subsequent glycan profiling by means of lectin-affinity technologies.

Journal

• SEIBUTSU BUTSURI KAGAKU

  SEIBUTSU BUTSURI KAGAKU 48 (1), 11-17, 2004

  Japanese Electrophoresis Society

Keywords

• glycoproteomics
• glycan profiling
• glyco-catch method
• lectin

Details

• CRID: 1390001204201770112
• NII Article ID: 10012842261
• NII Book ID: AN00129729
• DOI: 10.2198/sbk.48.11
• ISSN: 13499785
• ISSN: 00319082
• NDL BIB ID: 6894420
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6894420
• Web Site: https://search.jamas.or.jp/link/ui/2005215653
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed