Characteristics of atherosclerosis in long-term survivors on maintenance hemodialysis

この論文にアクセスする

この論文をさがす

著者

    • Kuramochi Gen KURAMOCHI Gen
    • Dept. of Internal Medicine, Kariwa-gun General Hospital, The Niigata Prefectural Federation of Agricultural Cooperatives for Health and Welfare

抄録

Accelerated atherosclerosis has come to pose a great threat to the lives of hemodialysis patients. In the present study, to determine the characteristics of atherosclerosis in long-term survivors on maintenance hemodialysis (mean age : 57±3 years, mean duration of hemodialysis : 279±11 months), the reference to clinical, biochemical and physiological parameters pertaining to atherosclerosis were examined and the results were compared with those in age-matched short-term hemodialysis patients (mean age : 55±2 years, mean duration of hemodialysis : 23±3 months). Although hypertension is regarded as one of cardiovascular risk factors together with diabetes, smokings and hyperlipidemia, our study found that the incidence of hypertension was significantly lower in long-term survivors on hemodialysis (16.7%) than in short-term hemodialysis patients (83.3%). However, no significant differences in biochemiacal data and carotid artery intima-media thickness were found between the two groups of hemodialysis patients. Levels of pulse wave velocity (PWV) in both short-term hemodialysis patients (1912±165 cm/sec) and long-term survivors on hemodialysis (1627±97 cm/ sec) were significantly higher than those in age-matched healthy subjects (1382±44 cm /sec). The levels of PWV in long-term survivors on hemodialysis tended to be lower than those in short-term hemodialysis patients, although the difference was statistically not significant. These results suggest that atherosclerotic alterations have already advanced in non-dialyzed patients with end-stage renal disease. The relatively lower levels of PWV in long-term survivors on hemodialysis may reflect the higher incidence of cardiovascular-related complications in those patients with highly accelerated atherosclerosis who die or may drop out during hemodialysis treatment.

収録刊行物

  • 日本農村医学会雑誌

    日本農村医学会雑誌 52(6), 992-1000, 2004-03-30

    THE JAPANESE ASSOCIATION OF RURAL MEDICINE

参考文献:  38件中 1-38件 を表示

各種コード

  • NII論文ID(NAID)
    10012862945
  • NII書誌ID(NCID)
    AN00196216
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    04682513
  • NDL 記事登録ID
    6915929
  • NDL 雑誌分類
    ZS17(科学技術--医学--衛生学・公衆衛生)
  • NDL 請求記号
    Z19-224
  • データ提供元
    CJP書誌  NDL  J-STAGE 
ページトップへ