A CASE OF ENDOCRINE CELL CARCINOMA OF THE RECTUM

• YAMAUCHI Kimi

  Departments of Surgery, Gifu Prefectural Gero Hot Spring Hospital

• MIYATA Tomoyuki

  Departments of Surgery, Gifu Prefectural Gero Hot Spring Hospital

• OKADA Naomasa

  Departments of Surgery, Gifu Prefectural Gero Hot Spring Hospital

• NITTA Toyoo

  Departments of Surgery, Gifu Prefectural Gero Hot Spring Hospital

• KAWAI Hisakazu

  Departments of Surgery, Gifu Prefectural Gero Hot Spring Hospital

• MIYASITA Takehiko

  Departments of Pathology, Gifu Prefectural Gero Hot Spring Hospital

Bibliographic Information

Other Title

• 直腸内分泌細胞癌の１例

Abstract

A 78-year-old man was seen at the hospital because of general fatigue, appetite loss and anal bleeding. Colonoscopic examination showed a type 1 tumor in the lower rectum and the histological diagnosis from a biopsy specimen was poorly or undifferentiated adenocarcinoma. Multiple liver metastases were discovered by abdominal computed tomography (CT). Abdomino-perineal amputation of the rectum and reservoir implantation were performed. Immunohistochemically the resected specimen was positive for chromograine A and NSE stain. The definite diagnosis was endocrine cell carcinoma. Chemotherapy was started but the patient died 6 months after the surgery.<br>Endocrine cell carcinoma has malignant potential and discrimination from poorly or undifferentiated adenocarcinoma is difficult. In a review of the Japanese literature 37 cases of neuroendorine tumors of the rectum have been reported. Of the 37 cases, liver metastasis was confirmed in 22 cases before surgery. Five cases were early carcinoma but the prognosis of them was poor. It is thought that the prognosis is not related to infiltration depth. Endocrine cell carcinoma has a very poor prognosis and effective multimodal therapy including operation and chemoradiotherapy should be established.

Journal

• Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)

  Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 65 (3), 751-755, 2004

  Japan Surgical Association

Keywords

• 内分泌細胞癌
• 直腸

Details

• CRID: 1390001204843447168
• NII Article ID: 10012865421
• NII Book ID: AA11189709
• DOI: 10.3919/jjsa.65.751
• ISSN: 18825133
• ISSN: 13452843
• Web Site: http://www.jstage.jst.go.jp/article/ringe1998/65/3/65_3_751/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2004185749
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed