Ｌａｃｔｏｂａｃｉｌｌｕｓ　ｐｌａｎｔａｒｕｍを用いて調製した発酵乳の生理機能　Ｉ　　Ｌａｃｔｏｂａｃｉｌｌｕｓ　ｐｌａｎｔａｒｕｍの大腸到達性および健康成人の糞便細菌叢に及ぼす影響

• 久米村 恵

  大塚製薬 (株) 大津栄養製品研究所

• 戸羽 正道

  大塚製薬 (株) 大津栄養製品研究所

• 曽川 芳郎

  大塚製薬 (株) 大津栄養製品研究所

• 清水 精一

  大塚製薬 (株) 消費者製品開発部P-14プロジェクト

• 川口 信三

  久留米大学医学部第一内科

書誌事項

タイトル別名

• Physiological Function of Lactobacillus plantarum Fermented Milk. I. Survival of Lactobacillus plantarum Species in the Gastrointestinal Tract and the Effect on Fecal Microflora in Human.
• Survival of <I>Lactobacillus plantarum</I> Species in the Gastrointestinal Tract and the Effect on Fecal Microflora in Human
• <I>Lactobacillus plantarum</I>の大腸到達性および健康成人の糞便細菌叢に及ぼす影響

抄録

The ability to survive of Lactobacillus plantarum ONC141 strain in the gastrointestinal tract andthe effect of administration of L. plantarum fermented milk on fecal microflora in human were studied. Six healthy subjects consumed 200 ml of fermented milk containing 5.3×10⁸ CFU of L. plantarum ONC141 strain per ml for seven days. L. plantarum ONC141 strain was enumerated in fresh feces before (day 0) and after ingestion (days 1, 2, 4, 7). L. plantarum ONC141 strain was not detected at day 0, but averaged 10⁷-10⁸CFU per gram feces for the other days. Twenty-one healthy subjects were divided into 2 groups that consumed for 4 weeks either 300 ml of fermented milk containing 7.1×10⁷CFU of L. plantarum ONC141 strain per ml (11 subjects) or 300 ml of commercial cow's milk (10 subjects). Fecal samples were collected before and after the ingestion period and the fecal microflora was analyzed. The numbers of fecal lactobacilli and bifidobacteria increased significantly in individuals given fermented milk with L. plantarum ONC141 strain and were significantly higher than those detected in individuals fed commercial cow's milk. In addition, thepercentage of bifidobacteria was remarkably increased by ingestion of fermented milk (from 21% to 44% of total counts). These results demonstrate that L. plantarum ONC141 strain in the fermented milk can survive in the human gastrointestinal tract, and alter the composition of the fecal microflora, in a manner consistent with providing beneficial effects for human health.

収録刊行物

• 腸内細菌学雑誌

  腸内細菌学雑誌 15 (1), 15-20, 2001

  公益財団法人 腸内細菌学会

キーワード

• <I>Lactobacillus plantarum</I>
• fecal microflora
• fermented milk

詳細情報

• CRID: 1390282679327988608
• NII論文ID: 130003869470
• NII論文ID: 10013032422
• NII書誌ID: AA11373504
• DOI: 10.11209/jim1997.15.15
• ISSN: 13498363
• ISSN: 13430882
• Web Site: https://search.jamas.or.jp/link/ui/2002024677
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可