ケアハウス入居高齢者における骨代謝と１日歩行数・握力との関連

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タイトル別名
  • Bone Metabolism, Daily Walking Amount and Grip Strength in Old People
  • ケアハウス ニュウキョ コウレイシャ ニ オケル コツ タイシャ ト 1ニチ ホコウスウ アクリョク ト ノ カンレン

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The relationship between bone metabolism, physical activity level and muscle strength was investigated in 27 men and 68 women with a mean age of 80 years. After the daily nutritional intake and walking amount had been recorded for one week, fasting blood and second urine samples were collected early in the morning, and the body height, weight, fat percentage and grip strength were measured. In addition, the index of bone mineral density was evaluated by quantitative ultrasound to determine the speed of sound (SOS) in the right calcaneus. The following blood and urinary markers of bone turnover were measured: serum bone-specific alkaline phosphatase (BAP) and osteocalcin (OC) for bone formation, and urinary crosslinked N-telopeptides of type I collagen (NTx) and deoxypiridinoline (DPD) for bone resorption. The SOS level was significantly lower, while the OC, NTx and DPD levels were significantly higher in the women than in the men, suggesting a higher bone turnover in the women. Significant negative correlations were observed in the women between the grip strength and both the NTx and DPD levels. Furthermore, the NTx level was significantly higher in the low-grip-strength group (25 percentile low-ranking) than in the 25 percentile high-ranking group, while the lean body mass and daily walking amount were significantly lower in the medium- and low-grip-strength groups. These results demonstrate that maintaining muscle strength may suppress the increased bone resorption in older women.

収録刊行物

  • 栄養学雑誌

    栄養学雑誌 62 (3), 145-151, 2004

    特定非営利活動法人 日本栄養改善学会

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