アスピリン喘息に対する内視鏡下鼻副鼻腔手術の効果

  • 藤井 可絵
    大阪労災病院耳鼻咽喉科
  • 田村 学
    大阪大学大学院医学系研究科感覚器外科学耳鼻咽喉科
  • 西池 季隆
    市立吹田市民病院耳鼻咽喉科
  • 大崎 康宏
    大阪大学大学院医学系研究科感覚器外科学耳鼻咽喉科
  • 久保 武
    大阪大学大学院医学系研究科感覚器外科学耳鼻咽喉科

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タイトル別名
  • Effect of Endoscopic Sinus Surgery on Aspirin-induced Asthma

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There have been little evaluation of the effectiveness of endoscopic sinus surgery (ESS) in AIA patients with chronic sinusitis. Using objective and subjective criteria, we assessed the effect of ESS on nasal and asthmatic symptoms in 12 AIA patients and in 8 non-AIA patients.<br>Objective evaluation for chronic sinusitis was assessed by CT finding and the number of eosinophils. The evaluation by Kennedy staging showed that postoperative CT findings did not differ from preoperative ones. The numbers of eosinophils in the postoperative nasal cavity did not differ from those in nasal polyps obtained during surgery. The airway of individual nasal cavities was, however, kept open. Subjective nasal symptoms were significantly improved after ESS.<br>Objective evaluation for asthma was assessed by pulmonary function tests and the amount of antiasthma medication. Pulmonary function tests showed no improvement after ESS, and medication scores for asthma did not change. Although objective improvement was not obtained, subjective asthmatic symptoms improved significantly.<br>Subjective evaluation showed that ESS was effective in both nasal and asthmatic conditions. Our results suggest that the quality of life in AIA patients will be improved by ESS.

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