Two cases of Ewing's sarcoma of jaws.

  • Seki Katsunori
    First Depertment of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • Fukuta Yoshiyasu
    First Depertment of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • Ohya Takanori
    First Depertment of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • Yokota Mitsumasa
    First Depertment of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • Ishikawa Yoshihito
    First Depertment of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • Matsuda Atsushi
    First Depertment of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • Takeda Yasunori
    Department of Oral Pathology, School of Dentistry, Iwate Medical University
  • Kudo Keigo
    First Depertment of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University

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  • 顎骨に発生したEwing肉腫の2例

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Abstract

Two patients with Swing's sarcoma of the jaw were reported.<BR>Case 1 was a 7-year-old female with the chief complaints of an expanding mass and pressure pain of the right mental region. The clinical diagnosis was osteogenic sarcoma, but histopathologically Ewing's sarcoma. The tumor of the mental region was 38×30 mm in size. Mandibular resection following preoperative chemotherapy of MTX and doxorubicin [AD] was carried out. In spite of the postoperative radiotherapy of 60Co 27Gy with administration of vincristine [VC], actionomycin D [AC] and cyclophosphamide [CP], she died due to brain metastasis 10 months later.<BR>Case 2 was a 2-year-old male with the chief complaint of a swelling in the anterior region of the maxilla. The tumor located in the bilateral incisal region of the maxilla was 27×34mm in size. The clinical diagnosis was suspicted malignant tumor, and histopathologic examination revealed Ewing's sarcoma. The patient was treated by irradiation of 60CO 35Gy with chemotherapy of VAC regimen [VC, AC, CP] . He died due to pulmonary metastasis 4 years and 2 months after the initial diagnosis.<BR>Both patients with primary lesion of upper and lower jaws had been well controlled clinically, but died because of uncontrollable distant metastases.

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