Effect of Static Magnetic Field on Cell Migration

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  • Hashimoto Yuichiro
    Tokyo Denki University Department of Information and Communication Engineering
  • Kawasumi Masashi
    Tokyo Denki University Department of Information and Communication Engineering
  • Saito Masao
    Tokyo Denki University Department of Information and Communication Engineering

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Other Title
  • 静磁界曝露の細胞移動への影響
  • セイ ジカイ バクロ ノ サイボウ イドウ エ ノ エイキョウ

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Abstract

The effect of magnetic field on cell has long been investigated, but there are few quantitative investigations of the migration of cells. Cell-migration is important as one of the fundamental activities of the cell. This study proposes a method to evaluate quantitatively the cell-diffusion constant and the effect of static magnetic field on cell migration. The cell-lines are neuroblastoma (NG108-15), fibroblastoma (NIH/3T3) and osteoblastoma (MC3T3-E1). The static magnetic field of 30 mT or 120 mT is impressed by a permanent magnet in vertical or horizontal direction to the dish. It is shown that the cell-diffusion constant can represent the cell migration as the cell activity. It is found that the cell migration is enhanced by exposure to the magnetic field, depending on the kind of cell. It is conjectured that the effect of static magnetic field affects the cell migration, which is at the downstream of the information transmission.

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