The Timing of the Reflected Wave in the Ascending Aortic Pressure Predicts Restenosis after Coronary Stent Placement

• UEDA Hiroyasu

  Department of Cardiology, Ishikiriseiki Hospital

• HAYASHI Tomoshige

  Department of Preventive Medicine and Environmental Health, Osaka City University Graduate School of Medicine

• TSUMURA Kei

  Department of Center for General Medicine, Osaka City University Graduate School of Medicine

• YOSHIMARU Kiyomichi

  Department of Cardiology, Ishikiriseiki Hospital

• NAKAYAMA Yasunori

  Department of Cardiology, Ishikiriseiki Hospital

• YOSHIKAWA Junichi

  Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine

抄録

It has been reported that the reflection waveform in the ascending aortic pressure is associated with systemic arterial stiffness. Stiffening of the aortic walls leads to a decrease in coronary perfusion and an increase in restenosis rate. The purpose of this study was to evaluate whether the reflection waveform in the ascending aortic pressure could be used to predict restenosis after percutaneous coronary stenting. One hundred and three patients who underwent percutaneous coronary stenting were enrolled in this study. We measured the inflection time and augmentation index (AIx) to determine the reflection waveform in the ascending aortic pressure at angioplasty. We then prospectively investigated the effect of inflection time and AIx in relation to the subsequent risk of restenosis after coronary stenting. After adjustments for age, gender, smoking habits, hypertension, type 2 diabetes, hypercholesterolemia, stent size, and heart rate, the odds ratio of restenosis in inflection time was 4.62 (95% confidence interval (CI), 1.39 to 15.4) for the lowest tertile of the inflection time level compared with the highest tertile level. As for AIx, the odds ratio of restenosis was 6.96 (95% CI, 1.93 to 25.1) for the highest tertile of the AIx level compared with the lowest tertile level. Inflection time and AIx are related to restenosis after percutaneous coronary stenting. (Hypertens Res 2004; 27: 535-540)

収録刊行物

• Hypertension Research

  Hypertension Research 27 (8), 535-540, 2004

  日本高血圧学会

キーワード

• <B>inflection time</B>
• <B>augmentation index</B>
• <B>predictor</B>
• <B>restenosis</B>
• <B>stent</B>

詳細情報

• CRID: 1390282679696947840
• NII論文ID: 10013604047
• NII書誌ID: AA10847079
• DOI: 10.1291/hypres.27.535
• ISSN: 13484214
• ISSN: 09169636
• PubMed: 15492471
• Web Site: https://search.jamas.or.jp/link/ui/2005128537
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可