漢方薬による肝障害に対する薬物性肝障害診断基準の感度と特異度

• 萬谷 直樹

  群馬大学医学部統合和漢診療学講座 富山医科薬科大学医学部和漢診療学講座

• 小暮 敏明

  群馬大学医学部統合和漢診療学講座

• 貝沼 茂三郎

  富山医科薬科大学医学部和漢診療学講座

• 嶋田 豊

  富山医科薬科大学医学部和漢診療学講座

• 寺澤 捷年

  富山医科薬科大学

書誌事項

タイトル別名

• Kampo medicine and new criteria for diagnosis of drug-induced liver injury: Sensitivity and specificity

抄録

Sensitivity and specificity of the new criteria for the diagnosis of drug-induced liver injury were examined among patients taking Kampo medicines. Examining the summaries of all admission records of patients from 1979 to 1999 in our department, we selected 30 summaries that described liver disorders suspected of being related to Kampo medicines. Causal relationship between lever injury and Kampo medicine was reexamined in each case. Specificity was examined using definitely unrelated group (8 cases), and sensitivity was examined using probably (2 cases) and definitely (4 cases) related groups. The sensitivity was 100% for the all criteria. The specificity was low for the all criteria, and was 25% for the original DDW-J criteria. These results suggest that the DDW-J criteria may be unreliable for the diagnosis of Kampo-medicine-induced liver injury.

収録刊行物

• 肝臓

  肝臓 45 (7), 345-349, 2004

  一般社団法人　日本肝臓学会

キーワード

• 薬物性肝障害
• 診断基準
• 漢方薬
• 感度
• 特異度

詳細情報

• CRID: 1390001204790971520
• NII論文ID: 10013762017
• NII書誌ID: AN00047770
• DOI: 10.2957/kanzo.45.345
• ISSN: 18813593
• ISSN: 04514203
• ISSN: http://id.crossref.org/issn/04514203
• Web Site: http://www.jstage.jst.go.jp/article/kanzo1960/45/7/45_7_345/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2004309854
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可