The Role of Interleukin-9 in Asthma

• Hauber Hans-Peter

  Meakins-Christie Laboratories, McGill University

• Hamid Qutayba

  Meakins-Christie Laboratories, McGill University

抄録

Interleukin (IL)-9 is a pleiotropic Th2 type cytokine which has been shown to play an important role in the pathogenesis of bronchial asthma. This review will concentrate on the structure, the source, and the effects of IL-9 as well as its induction and inhibition. The signaling of IL-9 through its receptor will be outlined. Moreover the role of IL-9 in airway hyperresponsiveness, mucus overproduction and airway remodeling in bronchial asthma will be discussed. Possible treatment options by blocking IL-9 will be outlined.<br>

収録刊行物

• Allergology International

  Allergology International 54 (1), 71-78, 2005

  一般社団法人日本アレルギー学会

キーワード

• airway hyperresponsiveness
• asthma
• interleukin-9
• interleukin-9 receptor
• mucus overproduction

詳細情報

• CRID: 1390001204631191168
• NII論文ID: 10014468709
• NII書誌ID: AA11091750
• DOI: 10.2332/allergolint.54.71
• ISSN: 14401592
• ISSN: 13238930
• Web Site: http://api.elsevier.com/content/article/PII:S132389301531008X?httpAccept=text/xml
• Web Site: http://api.elsevier.com/content/article/PII:S132389301531008X?httpAccept=text/plain
• Web Site: https://search.jamas.or.jp/link/ui/2006305138
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可