Alpha-fetoprotein (AFP)- and Des-gamma-carboxy Prothrombin (DCP)-producing Adenocarcinoma of the Stomach with Liver Metastasis in a Patient with Chronic Hepatitis C

• SOHDA Tetsuro

  Third Department of Medicine, Fukuoka University, School of Medicine

• TOMIOKA Yoshitaka

  Third Department of Medicine, Fukuoka University, School of Medicine

• INOMATA Shinjiro

  Third Department of Medicine, Fukuoka University, School of Medicine

• MORITA Isamu

  Third Department of Medicine, Fukuoka University, School of Medicine

• EGUCHI Koichi

  Third Department of Medicine, Fukuoka University, School of Medicine

• AOYAGI Kunihiko

  Third Department of Medicine, Fukuoka University, School of Medicine

• WATANABE Hiroshi

  Third Department of Medicine, Fukuoka University, School of Medicine

• NAKAMURA Shotaro

  Nakamura Gastrointestinal Clinic, Fukuoka

• SAKISAKA Shotaro

  Third Department of Medicine, Fukuoka University, School of Medicine

抄録

A 45-year-old man was admitted to our hospital because of chronic hepatitis C and a large liver tumor accompanied by increased serum levels of alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP), the tumor markers for hepatocellular carcinoma. Endoscopic examination revealed advanced gastric cancer. Biopsy specimens of the stomach and liver showed gastric adenocarcinoma and its metastasis to the liver. Immunohistochemical studies demonstrated that adenocarcinoma cells both of the stomach and liver, were positive for the antibodies against AFP as well as DCP. Expression of AFP mRNA was shown in the cancer cells of the stomach. Accordingly, we diagnosed this patient with AFP- and DCP-producing adenocarcinoma of the stomach together with liver metastasis.

収録刊行物

• Internal Medicine

  Internal Medicine 44 (4), 294-298, 2005

  一般社団法人 日本内科学会

キーワード

• alpha-fetoprotein (AFP)
• AFP mRNA
• des-gamma-carboxy prothrombin (DCP)
• gastric cancer
• hepatitis C virus (HCV)
• immunohistochemistry

詳細情報

• CRID: 1390001204868915072
• NII論文ID: 10015461769
• NII書誌ID: AA10827774
• DOI: 10.2169/internalmedicine.44.294
• ISSN: 13497235
• ISSN: 09182918
• NDL書誌ID: 7301501
• PubMed: 15897638
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7301501
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/44/4/44_4_294/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2006033330
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可