著明な血小板減少を来したマムシこう傷の1例

  • 藤田 基
    山口大学医学部附属病院先進救急医療センター
  • 山下 進
    山口大学医学部附属病院先進救急医療センター
  • 河村 宜克
    山口大学医学部附属病院先進救急医療センター
  • 鶴田 良介
    山口大学医学部附属病院先進救急医療センター
  • 笠岡 俊志
    山口大学医学部附属病院先進救急医療センター
  • 岡林 清司
    山口大学医学部附属病院先進救急医療センター
  • 前川 剛志
    山口大学医学部附属病院先進救急医療センター

書誌事項

タイトル別名
  • Viper (Agkistrodon halys blomhoffii "Mamushi") Bite with Remarkable Thrombocytopenia

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We report a patient with a viper (Agkistrodon halys Blomhoffii “Mamushi”) bite who developed remarkable thrombocytopenia. A 72-year-old woman who had been bitten by a mamushi on her right lower extremity was transferred to our emergency department because of remarkable thrombocytopenia and hemorrhagic diathesis. Hematemesis, conjunctival hemorrhage and subcutaneous hemorrhage were observed. However, her right lower extremity was not swollen remarkably. The laboratory findings revealed remarkable thrombocytopenia (thrombocyte: 0.3×104/mm3). However, coagulation tests, except for the platelet count, were within the normal ranges. Mamushi antivenom (6, 000U) was administrated intravenously. After the administration of the antivenom, the thrombocyte count gradually increased. Four hours later, the patient's thrombocyte level had normalized and her bleeding tendency had improved. The swelling on her right foot did not spread. She recovered and was transferred to another hospital on the 14th hospital day. Remarkable thrombocytopenia without massive tissue necrosis and DIC after a mamushi bite is rare. In almost all mamushi-bite cases, the symptoms are caused by mamushi venom in the local tissue. In the present case, however, the mamushi venom may have penetrated a major blood vessel. We recommend that mamushi antivenom should be administrated intravenously when remarkable thrombocytopenia is observed.

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