書誌事項
- タイトル別名
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- Drug use investigation of azithromycin
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We conducted a drug use investigation of azithromycin -Zithromac® Tablets 250mg, Zithromac Fine Granules for Pediatric Use, and Zithromac ® Capsules for Pediatric Use 100 mg for 3 years from 2000. We collected reports on 4, 622 cases from 278 medical institutions nationwide and evaluated safety and efficacy of azithromycin in 3, 745 cases subject to safety analysis and 3, 126 cases subject to efficacy analysis.<BR>The incidence of adverse reactions was 2.40%(90 /3, 745). Major adverse reactions included 30 cases of diarrhea, 15 of vomiting, 11 of increased alanine aminotransferase (ALT), 7 of increased aspartate aminotransferase (AST), and 6 of nausea.<BR>Efficacy by to indication was 82.0%(418/510) for adult dermatological infection, 82.0%(858/1, 046) for adult respiratory tract infection, 80.0%(92/115) for adult sinusitis, 89.4%(320 358) for adult dental /oral infection, 80.8%(813/1, 006) for pediatric respiratory tract infection, and 69.2%(63/91) for pediatric otitis media.<BR>Compliance by dosage form-patients who took the drug following the instruction provided-was 97.5%(2, 312/2, 372) for tablets, 93.5%(1, 128/1, 206) for fine granules, and 97.1%(133/137) for capsules.<BR>Results were favorable for safety, efficacy, and compliance.
収録刊行物
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- 日本化学療法学会雑誌
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日本化学療法学会雑誌 53 (5), 313-325, 2005
公益社団法人 日本化学療法学会
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詳細情報 詳細情報について
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- CRID
- 1390001206284519680
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- NII論文ID
- 130004298256
- 10015650561
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- NII書誌ID
- AN10472127
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- ISSN
- 18845886
- 13407007
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可