総合健診長期反復受診者の縦断調査　　耐糖能障害発症に及ぼす因子の検討

• 奥田 克子

  愛知県総合保健センター

• 津下 一代

  愛知県総合保健センター あいち健康の森健康科学総合センター

• 岩塚 徹

  愛知県総合保健センター あいち健康の森健康科学総合センター

書誌事項

タイトル別名

• Natural Course of Type 2 Diabetes. A Longitudinal Study of Health Check-up Data for More Than Ten Years.
• —A Longitudinal Study of Health Check-up Data for More Than Ten Years—
• ―耐糖能障害発症に及ぼす因子の検討―

抄録

Type 2 Diabetes has enormously increased for the last few decades in Japan. It is one of the life-style related diseases and prevention is thought to be very important to reduce it. We examined health check-up data longitudinally and tried to reveal the risk factors and find the natural course of the onset of the disease. Normal fasting plasma glucose (FPG) group (n=11, 123, age: 41.9±7.1) have been followed up for more than 10 years. Among them, 8.6% became diabetes (DM group, FPG≥126 mg/dl) and 24.9% became Impaired Glucose Tolerance (IGT group, 110≤FPG<126) in 14 years. DM group and IGT group had significantly high FPG, BMI, ALT and triglyceride level during the observation period. Multiple regression tests (Stepwise method) revealed the significant relation between the last FPG value and FPG initial, BMI, ALT and triglyceride. According to Cox model, FPG level initial might be crucial, even if it was within normal range. If FPG were from 90 to 94 mg/dl, 10% would become diabetes in next two decades, but if FPG were from 105 to 109 mg/dl, 46% would become diabetes in the same period.

収録刊行物

• 日本総合健診医学会誌

  日本総合健診医学会誌 28 (4), 434-438, 2001

  一般社団法人 日本総合健診医学会

キーワード

• 総合健診
• 縦断調査
• 耐糖能障害
• 空腹時血糖
• 糖尿病

詳細情報

• CRID: 1390001204714033920
• NII論文ID: 130004062420
• NII論文ID: 10016119641
• NII書誌ID: AN10040585
• DOI: 10.7143/jhep1985.28.434
• ISSN: 1884409X
• ISSN: 09111840
• Web Site: https://search.jamas.or.jp/link/ui/2002110161
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可