小児急性リンパ性白血病に対する移植前全身照射法の実態

• 鈴木 信寛

  札幌医科大学医学部小児科 小児白血病研究会 (JACLS) 移植小委員会

• 原 純一

  小児白血病研究会 (JACLS) 移植小委員会

• 茶山 公祐

  小児白血病研究会 (JACLS) 移植小委員会

• 秋山 祐一

  小児白血病研究会 (JACLS) 移植小委員会

• 中畑 龍俊

  小児白血病研究会 (JACLS) 移植小委員会

書誌事項

タイトル別名

• Current Status of Total Body Irradiation in Conditioning Regimen for Childhood Acute Lymphoblastic Leukemia; Survey in the Japan Association of Childhood Leukemia Study (JACLS) Group

抄録

We surveyed methods of total body irradiation (TBI) in conditioning regimens of stem cell transplantation (SCT) for children with acute lymphoblastic leukemia (ALL) at participating institutions of the Japan Association of Childhood Leukemia Study (JACLS) ALL-97 protocol. We obtained information about TBI from 25 institutions. Total dose of 12 Gy fractionated by four to six in two to three days for TBI was conducted in 22 of 25 institutions. High-risk patients, such as patients with Philadelphia positive ALL, received over 12 Gy in five institutions. Beam direction and patient's positioning were horizontal and lateral respectively in 15 institutions. Shielding of lung and/or eyes and boost irradiation to central nervous system and/or testis were done in 24 and 11 institutions respectively, but in various ways. We have to keep in mind that a great variety of TBI have been undergone in each institution when we intend to interpret multi-institutional trials of treatment including SCT for patients with ALL.

収録刊行物

• 日本小児血液学会雑誌

  日本小児血液学会雑誌 19 (3), 131-136, 2005

  特定非営利活動法人　日本小児血液・がん学会

キーワード

• acute lymphoblastic leukemia
• stem cell transplantation
• conditioning regimen
• total body irradiation

詳細情報

• CRID: 1390282679318909952
• NII論文ID: 10016462405
• NII論文ID: 130004345854
• NII書誌ID: AN10080852
• DOI: 10.11412/jjph1987.19.131
• ISSN: 18844723
• ISSN: 09138706
• Web Site: https://search.jamas.or.jp/link/ui/2005262859
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可