Beneficial Effect of Preinfarction Angina on In-Hospital Outcome is Preserved in Elderly Patients Undergoing Coronary Intervention for Anterior Acute Myocardial Infarction

• Kosuge Masami

  Division of Cardiology, Yokohama City University Medical Center

• Kimura Kazuo

  Division of Cardiology, Yokohama City University Medical Center

• Kojima Sunao

  Department of Cardiovascular Medicine, Kumamoto University School of Medicine

• Sakamoto Tomohiro

  Department of Cardiovascular Medicine, Kumamoto University School of Medicine

• Ishihara Masaharu

  Department of Cardiology, Hiroshima City Hospital

• Asada Yujiro

  First Department of Pathology, Miyazaki University School of Medicine

• Tei Chuwa

  The First Department of Internal Medicine, Kagoshima University Faculty of Medicine

• Miyazaki Shunichi

  Division of Cardiology, Department of Internal Medicine, National Cardiovascular Center

• Sonoda Masahiro

  The Second Department of Cardiology, National Hospital Kyusyu Cardiovascular Center

• Tsuchihashi Kazufumi

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• Yamagishi Masakazu

  Division of Cardiology, Department of Internal Medicine, National Cardiovascular Center

• Ikeda Yoshihiko

  Department of Pathology, National Cardiovascular Center

• Shirai Mutsunori

  Department of Microbiology, School of Medicine, Yamaguchi University

• Hiraoka Hisatoyo

  Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University

• Inoue Takeshi

  Division of Cardiology, Oita National Hospital

• Saito Fumio

  Department of Cardiology, Nihon University Surugadai Hospital

• Ogawa Hisao

  Department of Cardiovascular Medicine, Kumamoto University School of Medicine

• on behalf of the Japanese Acute Coronary Syndrome Study (JACSS) Investigators

抄録

Background Preinfarction angina improves survival after acute myocardial infarction (AMI) in nonelderly but not elderly patients in the thrombolytic era. However, it remains unclear whether preinfarction angina has a beneficial effect on clinical outcome in elderly patients undergoing percutaneous coronary intervention (PCI). Methods and Results The study group comprised 484 anterior AMI patients who were admitted within 24 h of onset and underwent emergency PCI. Patients were divided into 2 groups: those aged <70 years (nonelderly patients, n=290) and those aged ≥70 years (elderly patients, n=194). Angina within 24 h before AMI was present in 42% of nonelderly patients and in 37% of elderly patients. In nonelderly patients, preinfarction angina was associated with a lower in-hospital mortality rate (1% vs 7%, p=0.02). Similarly, in elderly patients, preinfarction angina was associated with a lower in-hospital mortality rate (6% vs 16%, p=0.03). Multivariate analysis showed that the absence of preinfarction angina was an independent predictor of in-hospital mortality in both nonelderly (odds ratio 4.20; 95% confidence interval (CI) 1.20-10.6; p=0.04) and elderly patients (odds ratio 3.04; 95%CI 1.06-18.1; p=0.04). Conclusions Angina within the 24 h before AMI is associated with better in-hospital outcomes in elderly and nonelderly patients. (Circ J 2005; 69: 630 - 635)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 69 (6), 630-635, 2005

  一般社団法人 日本循環器学会

キーワード

• Aging
• Angina pectoris
• Myocardial infarction
• Reperfusion

詳細情報

• CRID: 1390282680079810944
• NII論文ID: 10016625687
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.69.630
• ISSN: 13474820
• ISSN: 13469843
• ISSN: http://id.crossref.org/issn/13469843
• PubMed: 15914937
• Web Site: https://search.jamas.or.jp/link/ui/2006293315
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可