重症肝炎との関連性濃厚なE型肝炎ウイルスgenotype IV内の広域分布型一系統:鳥取,新潟,札幌から得られた3本の完全長および1本の準完全長HEV塩基配列

書誌事項

タイトル別名
  • A lineage of hepatitis E virus within genotype IV, associated with severe forms of hepatitis

この論文をさがす

抄録

We found a lineage of hepatitis E virus (HEV) within genotype IV, members of which were JSF-Tot03C, JSN-Sap-FH02C, JYN-Sap 01C, HE-JK4, JYN-Nii 02L, HE-JF3, HE-JA1, HE-JI4 from humans and swJ13-1 from swine, all from Japan. Interestingly, of 9 patients infected with the HEV of this lineage, 3 were with fulminant hepatitis, and another 3 were with considerably prolonged prothrombin time (17%, 40% and 44%). In addition, at least 6 patients showed bilirubin levels greater than 10 mg/dl. Although host factors (pregnancy for example) may contribute much to clinical phenotypes of HEV infections, our present results suggest that a viral factor may also play an important role therein.

収録刊行物

  • 肝臓

    肝臓 46 (6), 389-390, 2005

    一般社団法人 日本肝臓学会

被引用文献 (10)*注記

もっと見る

参考文献 (11)*注記

もっと見る

詳細情報

問題の指摘

ページトップへ