重症肝炎との関連性濃厚なE型肝炎ウイルスgenotype IV内の広域分布型一系統:鳥取,新潟,札幌から得られた3本の完全長および1本の準完全長HEV塩基配列
書誌事項
- タイトル別名
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- A lineage of hepatitis E virus within genotype IV, associated with severe forms of hepatitis
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We found a lineage of hepatitis E virus (HEV) within genotype IV, members of which were JSF-Tot03C, JSN-Sap-FH02C, JYN-Sap 01C, HE-JK4, JYN-Nii 02L, HE-JF3, HE-JA1, HE-JI4 from humans and swJ13-1 from swine, all from Japan. Interestingly, of 9 patients infected with the HEV of this lineage, 3 were with fulminant hepatitis, and another 3 were with considerably prolonged prothrombin time (17%, 40% and 44%). In addition, at least 6 patients showed bilirubin levels greater than 10 mg/dl. Although host factors (pregnancy for example) may contribute much to clinical phenotypes of HEV infections, our present results suggest that a viral factor may also play an important role therein.
収録刊行物
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- 肝臓
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肝臓 46 (6), 389-390, 2005
一般社団法人 日本肝臓学会
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詳細情報
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- CRID
- 1390001204789269120
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- NII論文ID
- 10016637591
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- NII書誌ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可