Constituents from the Stems of Hibiscus taiwanensis

    • WU Pei-Lin
    • Department of Chemistry, National Cheng Kung University
    • HE Cai-Xia
    • Department of Chemistry, National Cheng Kung University
    • SU Chia-Hao
    • Department of Chemistry, National Cheng Kung University
    • LEE Kuo-Hsiung
    • Natural Products Laboratory, School of Pharmacy, University of North Carolina

Abstract

Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9'-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 53(1), 56-59, 2005-01-01  [Table of Contents]

The Pharmaceutical Society of Japan

References:  33

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Cited by:  1

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Codes

  • NII Article ID (NAID) :
    10016651461
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • Article Type :
    Journal Article
  • ISSN :
    00092363
  • NDL Article ID :
    7200805
  • NDL Source Classification :
    ZS51(科学技術--薬学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No. :
    Z53-D167
  • DOI :
    10.1248/cpb.53.56
  • Databases :
    CJP  CJPref  NDL  NII-ELS  J-STAGE