In Vitro and in Vivo Antimicrobial Action of Tea: The Commonest Beverage of Asia
-
- Bandyopadhyay Durba
- Department of Pharmaceutical Technology, Jadavpur University
-
- Chatterjee Tapan Kumar
- Department of Pharmaceutical Technology, Jadavpur University
-
- Dasgupta Asish
- Department of Pharmaceutical Technology, Jadavpur University
-
- Lourduraja Jeyaseeli
- Department of Pharmaceutical Technology, Jadavpur University
-
- Dastidar Sujata Ghosh
- Department of Pharmaceutical Technology, Jadavpur University
この論文をさがす
抄録
The methanolic extract of leaves of Camellia sinensis (L) O. KUNTZE was screened for antimicrobial property against 111 bacteria comprising 2 genera of Gram positive and 7 genera of Gram negative bacteria. Most of these strains were inhibited by the compound at 10—50 μg/ml level and few strains were sensitive even at lower concentrations (5 μg/ml). The bacteria could be arranged in the decreasing order of sensitivity towards the compound in the following manner: Staphylococcus aureus, Vibrio cholerae, Escherichia coli, Shigella spp., Salmonella spp., Bacillus spp., Klebsiella spp. and Pseudomonas aeruginosa. The antibacterial activity of compound could also be confirmed in vivo. When it was given to Swiss strain of white mice at different dosages (30, 60 μg/mouse), it could significantly protect the animals challenged with 50 MLD of Salmonella typhimurium NCTC 74. According to Chi square test the in vivo data were highly significant (p<0.001).
収録刊行物
-
- Biological & Pharmaceutical Bulletin
-
Biological & Pharmaceutical Bulletin 28 (11), 2125-2127, 2005
公益社団法人 日本薬学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282679603387648
-
- NII論文ID
- 10016783700
-
- NII書誌ID
- AA10885497
-
- ISSN
- 13475215
- 09186158
-
- NDL書誌ID
- 7675766
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可