書誌事項
- タイトル別名
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- Generalized erythema triggered by a rapid decrease of basophils in chronic myeloid leukemia treated with imatinib
- メシルサン イマチニブ ニ ヨル キュウゲキ ナ コウエンキキュウ ゲンショウ オ ケイキ ニ ゼンシンセイコウ ハン オ テイシタ マンセイ コツズイセイ ハッケツビョウ
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抄録
A 57-year-old woman with chronic myeloid leukemia showing severe basophilia (WBC 17.1×109/L, basophils 23%) was treated with 400mg imatinib in June 2003. A high basophil count (WBC 10.6×109/L, basophils 31%) was still observed after 1 week of therapy. After 9 days of therapy, she developed generalized pruritic skin erythema, chills and high fever. After terminating imatinib treatment, prednisolone therapy was initiated. The rash quickly disappeared. Four days after withdrawal of imatinib, leukocyte count was 13.0×109/L with 3% of basophils, suggesting the possibility that rapid decrease in basophils following imatinib therapy may induce severe cutaneous reactions.
収録刊行物
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- 臨床血液
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臨床血液 46 (11), 1226-1228, 2005
一般社団法人 日本血液学会
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詳細情報 詳細情報について
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- CRID
- 1390282680007318400
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- NII論文ID
- 10016878506
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- NII書誌ID
- AN00252940
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- COI
- 1:STN:280:DC%2BD28%2Fls1Gksw%3D%3D
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- ISSN
- 18820824
- 04851439
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- NDL書誌ID
- 7748662
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可