Ｉｎｔｅｇｒａｔｅｄ　Ｂａｃｋｓｃａｔｔｅｒ解析を用いた頚動脈プラークの定量的超音波輝度測定

• 嶋田 裕史

  独立行政法人国立病院機構九州医療センター　臨床検査科臨床研究部

• 伊藤 美智子

  独立行政法人国立病院機構九州医療センター　臨床検査科臨床研究部

• 井上 =亨

  独立行政法人国立病院機構九州医療センター　脳血管センター　臨床研究部脳神経外科

• 藤本 茂

  独立行政法人国立病院機構九州医療センター　脳血管センター　臨床研究部脳血管内科

• 岡田 靖

  独立行政法人国立病院機構九州医療センター　脳血管センター　臨床研究部脳血管内科

書誌事項

タイトル別名

• Quantitative Evaluation of Carotid Plaque Echogenicity by Integrated Backscatter Analysis

抄録

Objective: CEA and CAS are done to treat carotid artery stenosis, but clear eligibility criteria have not been established. In this study we evaluated arterial plaque objectively by IBS analysis with an ultrasound machine with an AD function, and classified the types of arteriosclerotic lesions according to the AHA criteria. Methods: The ultrasoud machine employed was a sonos 5500 with a L7540 probe; system setting gain 50% compression 70% TGC 159 LGC 0). We compared the histopathology in a total of 121 locations using the IBS value in 40 patients (31 men, 7 women) who underwent CEA between May 2002 and September 2003, and calculated the IBS value for hemorrhage, lipid, fibrosis, and calcification. The AHA type distinction classified 24 cases (22 men, 2 women) between November 2003 and June 2004, and its utility was reviewed. Results: We recognized a significant difference between hemorrhage and lipid (P<0.05), lipid and fibrosis (P<0.0001), and fibrosis and calcification (P<0.0001). Each IBS calculated a value with 80% sensitivity: hemorrhage<39 dB, 39 dB≤lipid>45 dB, 45 dB≤ fibrosis<50 dB, 50 dB≤calcification. We carried out ultrasonic diagnosis of 24 case using these values and this yielded 10 cases of AHA Type VI, 4 cases of AHA Type Va, 3 cases of AHA Type Vc, and 4 cases of AHA type Vb. In 3 cases measurement was not possible because of an acoustic shadow due to calcification. Tissue diagnosis yielded 8 cases of AHA Type VI, 7 cases of AHA Type Va, 2 cases of AHA Type Vc, and 4 cases of AHA type Vb. The concordance rate became 86%. The results suggested that this examination is useful for CEA, and choice of stenting.

収録刊行物

• Neurosonology:神経超音波医学

  Neurosonology:神経超音波医学 18 (1), 24-28, 2005

  一般社団法人日本脳神経超音波学会

キーワード

• IBS (integrated backscatter)
• AHA (American Heart Association) histologic classification
• CEA (carotid endarterectomy)
• CAS (carotid artery stenting)
• ICA stenosis

詳細情報

• CRID: 1390282679396975872
• NII論文ID: 10017133142
• NII書誌ID: AN10236361
• DOI: 10.2301/neurosonology.18.24
• ISSN: 18843336
• ISSN: 0917074X
• Web Site: https://search.jamas.or.jp/link/ui/2006090017
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可