緑茶抽出物のStreptococcus anginosus groupに対する抗菌作用  [in Japanese] Antibacterial Activity of Green Tea Extracts against Streptococcus anginosus group  [in Japanese]

    • 北田 勝浩 KITADA Katsuhiro
    • 鹿児島大学大学院医歯学総合研究科発生発達生育学講座口腔保健推進学分野 Department of Preventive Dentistry, Kagoshima University Graduate School of Medical and Dental Sciences
    • 井上 昌一 INOUE Masakazu
    • 鹿児島大学大学院医歯学総合研究科発生発達生育学講座口腔保健推進学分野 Department of Preventive Dentistry, Kagoshima University Graduate School of Medical and Dental Sciences
    • 於保 孝彦 OHO Takahiko
    • 鹿児島大学大学院医歯学総合研究科発生発達生育学講座口腔保健推進学分野 Department of Preventive Dentistry, Kagoshima University Graduate School of Medical and Dental Sciences

Abstract

Streptococcus anginosus groupはヒト口腔の常在菌であり,口腔内はもとより全身の化膿性疾患と深くかかわっている.一方,茶葉にはさまざまな抗菌物質や薬効成分が含まれており,その抽出物は齲蝕や歯周病原性細菌に対する抗菌作用をもっている.今回,化膿性疾患原性菌であるS. anginosus groupに対する緑茶抽出物のもつ抗菌作用について検討を行った.S. anginosus group (Streptococcus anginosus 7株,streptococcus constellatus 3株,streptococcus intermedius 4株)を含む18株の口腔細菌について緑茶抽出物の抗菌活性を調べたところ,S. intermedius 3株およびS. constellatus 1株が感受性を示したが,S. anginosusについては全く認められなかった.次に,強い感受性を示した2つの菌種について増殖抑制試験および殺菌試験を行った.代表株として用いたS. constellatus NCTC 10708とS. intermedius K 201 Kの2株に対して緑茶抽出物の増殖抑制効果が認められ,またそれらの働きは殺菌的であった.

Streptococcus anginosus group comprises a part of the normal flora in the human mouth and is closely associated with pyogenic infectious diseases in various body sites. It has been demonstrated that various kinds of antibacterial and medicinal ingredients are contained in green tea leaves, and tea extracts have antimicrobial effects against cariogenic and periodontopathic bacteria. Here, we report the antibacterial effects of green tea extracts against S. anginosus group. Against the 18 strains of oral bacteria including S. anginosus group (S. anginosus, 7 strains; S. constellatus, 3 strains; S. intermedius, 4 strains), the antibacterial effects of green tea extracts were tested. Three strains of S. intermedius and one of S. constellatus were sensitive to tea extracts. However, no strains of S. anginosus showed sensitivity to the extracts. Next, we examined whether the effects of the extracts were bactericidal or bacteriostatic using two species of bacteria which showed strong sensitivity. Against the 2 strains of S. constellatus NCTC10708 and S. intermedius K201K, the extracts showed a growth inhibitiory effeet, and the effect was bactericidal.

Journal

Journal of dental health   [List of Volumes]

Journal of dental health 56(2), 132-136, 2006-04-30  [Table of Contents]

The Japanese Society for Dental Health

References:  16

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Cited by:  2

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Codes

  • NII Article ID (NAID) :
    10017425510
  • NII NACSIS-CAT ID (NCID) :
    AN00081407
  • Text Lang :
    JPN
  • Article Type :
    Journal Article
  • ISSN :
    00232831
  • NDL Article ID :
    7955175
  • NDL Source Classification :
    ZS44(科学技術--医学--歯科学・口腔外科学)
  • NDL Call No. :
    Z19-144
  • Databases :
    CJP  CJPref  NDL  NII-ELS 

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