無黄疸肝門部胆管癌の1切除例

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  • A RESECTED CASE OF NON-ICTERIC HILAR CHOLANGIOCARCINOMA

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An asymptomatic 70-year-old man was pointed out liver dysfunction at a medical checkup in January 2005, and consulted another hospital. Because intrahepatic biliary dilatation was revealed by abdominal ultrasonogram and CT scan, he was referred to our hospital in February. When he was first seen, he had no jaundice with the serum total bilirubin of 0.5mg/dL and liver enzymes within normal limits but showed elevated biliary enzyme levels; ALP of 580IU/L and γ-GTP of 191IU/L. On abdominal CT scan and endoscopic retrograde cholangiogram, he was diagnosed as having hilar cholangiocarcinoma of the left hepatic duct (B1), suggestive of intramural spreading of cancer toward the lower bile duct. In March 2005, he underwent left hepatectomy, coudate lobectomy and extrahepatic bile duct resection. The suspected intramural spreading of the common bile duct was pathologically comfirmed to be inflammatory wall thickness.<br> In a review of 12 reported cases of resected hillar cholangiocarcinoma without jaundice, any symptoms were seen in six (50%), elevated biliary enzyme in 12 (92%), and intrahepatic biliary dilatation in 11 (92%) cases. The cancer deeply invaded to subserosal layer (ss) or more in six (50%) cases.

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